Mitigation of SARS-CoV-2 Transmission at a Large Public University
Ranoa, Diana Rose E., et al. “Mitigation of SARS-CoV-2 Transmission at a Large Public University.” MedRxiv, June 9, 2022. Nature Communications 13, art. 3207. https://doi.org/10.1101/2021.08.03.21261548.
Abstract: In fall 2020, universities saw extensive transmission of SARS-CoV-2 among their populations, threatening the health of the university and surrounding communities and viability of in-person instruction. Here we report a case study at the University of Illinois at Urbana-Champaign, where a multimodal “SHIELD: Target, Test, and Tell” program, with other nonpharmaceutical interventions, was employed to keep classrooms and laboratories open. The program included epidemiological modeling and surveillance, fast/frequent testing using a novel low-cost and scalable saliva-based RT-qPCR assay for SARS-CoV-2 that bypasses RNA extraction, called covidSHIELD, and digital tools for communication and compliance. In fall 2020, we performed >1,000,000 covidSHIELD tests, positivity rates remained low, we had zero COVID-19-related hospitalizations or deaths amongst our university community, and mortality in the surrounding Champaign County was reduced more than 4-fold relative to expected. This case study shows that fast/frequent testing and other interventions mitigated transmission of SARS-CoV-2 at a large public university.